Biomedical Science

Progression through the drug development process ranges from characterization of the lead compound to in vivo efficacy studies. At TherapeUTex, our goal is to aid and guide the development of drug products and technologies through this development process by providing services including drug formulation and delivery, in vitro and in vivo preclinical and proof-of-concept studies, lab-scale formulation, stability studies, and production. State-of-the-art analytical technologies and facilities at TherapeUTex provide the necessary tools to deliver the trustworthy results our customers expect. Our scientists, together with collaborating scientists from academia and industry, provide broad expertise in the pharmaceutical and biotech fields, with the flexibility to customize projects tailored to our clients’ needs.

Services Offered

• Drug Formulation and Delivery
• Preclinical and Proof-of-Concept Studies
• Lab-Scale Formulation and Stability Testing
• Analytical Services
• In Vivo Modeling

The Mouse Genetic Engineering Facility (MGEF) provides expert advice and custom services to generate, cryopreserve, and rederive genetically engineered mice for understanding mammalian gene function and human disease. The MGEF serves as a central hub for mouse genetics at UT by providing precision mouse models and transgenic services, engaging in teaching, training, and collaborative projects, and undertaking research that supports the core’s mission. The facility is a key resource for researchers across various disciplines, including those studying alcohol addiction, neurodegeneration, immunology, cancer, and developmental disorders.

Services Offered

• Design and generation of precision mouse models
• Cryopreservation of mouse lines
• Cryorecovery of mouse models from repositories
• Embryo manipulation for -omic studies

The Microscopy & Flow Cytometry Facility is the unit responsible for providing access to advanced light microscopes, flow cytometers, and cell sorters for research and teaching at the University. The facility supports users from all disciplines, offering both standard and high-end instrumentation. In addition to assisted use, the facility provides training on equipment and consultations to help researchers optimize their use of the available tools. Staff scientists work closely with investigators, ensuring access to the expertise and resources needed for cutting-edge imaging research.

Services Offered

• Light microscopy
• Confocal and fluorescence microscopy
• Flow cytometry
• Cell sorting
• Analysis workstations
• Training in microscopy and flow cytometry techniques
• Consultation on experimental design for microscopy and flow cytometry studies

The Biomedical Imaging Center (BIC) is an interdisciplinary, multimodal imaging facility that supports human and preclinical imaging research at the University of Texas and the wider community. The BIC spans 3 locations in the Norman Hackerman (NHB) and the Health Discovery (HDB) Buildings on the UT campus and hosts a range of systems for MRI, PET, CT and optical imaging. The Center accommodates both independent and assisted use (for human MRI and PET/CT) is on its instruments and provides in-house training in scanner safety and operation for independent users. The facility also supports a range of task / response paradigms for functional MRI (fMRI) studies and provides back-end support for data archiving, management and common analyses.

Services Offered

• Basic, translational and clinical-research involving human or preclinical imaging
• Initial consultation on establishing an imaging research project or program at BIC
• Development / implementation of MRI / fMRI protocols on our 3T and 7T systems
• Ongoing project advice and technical support for the imaging systems and ancillary equipment
• Educational courses on imaging physics and technology
• Training in scanner safety including MRI Level 1 certification
• Training in scanner-operation for our systems including MRI Level 2 certification
• Assisted scanning on the Siemens Prisma, Siemens Vida and GE Discovery systems
• Post-study support for data archiving, management and common analyses

Services Offered

• Aqueous geochemistry analysis
• Sample preparation and chemical treatments
• Analysis of environmental and geological samples
• Collaboration on water and soil chemistry studies

The X-ray Diffraction Facility at UT Austin’s Department of Chemistry offers comprehensive X-ray diffraction services for single crystal and powder samples. Equipped with advanced diffractometers, the facility supports both academic and external research needs, providing options for user-operated and lab-assisted analysis. Through rigorous safety and instrument training, graduate-level researchers can gain access for independent sample analysis, contributing to studies across chemistry and materials science.

Services Offered

• Crystallographic analysis of solid materials
• Phase identification and quantification
• X-ray powder diffraction for materials research
• Training in XRD data interpretation and analysis

The Electron Paramagnetic Resonance Spectroscopy (EPR) Facility at UT Austin's Department of Chemistry features a Bruker EMX Plus spectrometer equipped for X-band and Q-band EPR, as well as ENDOR and variable temperature studies. This facility supports a wide range of research applications by providing researchers access to sophisticated EPR instrumentation and expertise. The facility is committed to facilitating advanced investigations into paramagnetic species, enhancing the understanding of materials at the molecular level.

Services Offered

• EPR spectroscopy for paramagnetic sample analysis
• Custom EPR experimental design
• Sample preparation and support for paramagnetic studies
• Training in EPR data collection and interpretation
• High-resolution spectrometers for a range of biological and material applications

The Nuclear Magnetic Resonance (NMR) Facility at UT Austin provides researchers with high-resolution spectroscopic capabilities for structural analysis of organic, inorganic, and biomolecular compounds. Equipped with a range of state-of-the-art NMR spectrometers, the facility supports applications in chemistry, materials science, and pharmaceutical research. Services include routine and advanced NMR experiments, data interpretation, and user training. The facility also offers expert consultation for customized experimental setups, ensuring researchers have the tools and expertise needed for detailed molecular characterization.

Services Offered

• High-resolution NMR spectroscopy
• Analysis of molecular structure and dynamics
• Customizable NMR experimental setups
• Training in NMR data interpretation and experimental design

Isotope Ratio Mass Spectrometry EA-ISOLINK – Delta V IRMS

Carbon and nitrogen isotopic composition of solid samples (sediment, soil, nutrient filters, tissues)

GASBENCH – Delta V IRMS

• Carbon and oxygen isotopic composition of carbonates
• Oxygen and hydrogen isotopic composition of water
• Carbon isotopic composition of dissolved inorganic carbon. GC-ISOLINK – Delta V IRMS
• Compound specific carbon, nitrogen and hydrogen isotopic compositions of fatty acids, alkanes, alcohols, amino acids

LC-ISOLINK – Delta Q IRMS

Carbon isotope composition of liquid phased compounds

Mass Spectrometry LC-Ion-Mobility-Quadrupole-Time-of-Flight-Mass-Spectrometry

Provide accurate mass detection, molecular discovery, and quantification of analytes, including but not limited to, proteins, metabolites, lipids and carbohydrates. Agilent 6560 LC/MS IM-QTOF.

Elemental and Nutrient Analysis LACHAT QUIKCHEM

Quantify nutrients (ammonium, nitrate, silicate, phosphate) in aqueous samples (seawater, river water, groundwater)

TOC/TDN

Total organic carbon and total dissolved nitrogen abundance measurements in aqueous samples (seawater, river water, groundwater)

Services Offered

• Analytical services for marine and environmental samples
• Coastal and marine ecosystem monitoring
• Sample analysis for chemical and biological parameters
• Collaborative research in marine science and oceanography

The Bureau of Economic Geology (BEG) at UT Austin is a leading research institute dedicated to advancing the understanding of energy resources, environmental systems, and geological processes. As the oldest research unit at UT, BEG integrates cutting-edge science with practical applications, supporting industry, government, and public interest in areas such as energy exploration, carbon storage, water resource management, and environmental sustainability. BEG's multidisciplinary teams conduct innovative research and provide expertise, facilities, and data resources that drive scientific discovery and inform policy. The Bureau’s collaborative environment enables impactful research with global reach and real-world applications.

Services Offered

• Energy and environmental research
• Geological sample and data resources
• Industry and government partnerships
• Policy research on sustainability
• Training for geoscience professionals