Improving Rigor and Reproducibility in Mouse Research
This class covers best practices for maintaining mouse colonies to promote rigor and reproducibility in experimental research. It is intended for lab staff, graduate students, postdocs, and undergraduates working on mouse projects.
The topics to be covered include:
- Importance of genetic background
- Reproduction, breeding, and genotyping
- Sizing mouse colonies
- Recordkeeping
- Genetic drift
- Tips
- Resources
Preferred or Prerequisite Skills:
No prerequisites, although an understanding of basic genetics is presumed.
William Shawlot (Director, Mouse Genetic Engineering Facility, CBRS)
William Shawlot received his Ph.D. from Baylor College of Medicine and completed his postdoctoral training with Richard Behringer at the M.D. Anderson Cancer Center. He served as an Assistant Professor in the Department of Genetics, Cell Biology, and Development at the University of Minnesota before joining the Texas A&M Institute for Genomic Medicine (TIGM). He led TIGM’s knockout mouse production efforts as part of the International Knockout Mouse Consortium program. He has more than 30 years of experience in the transgenic mouse field and serves on the External Advisory Committee for the NIH’s Mutant Mouse Resource and Research Center program.
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$10