The Sauer Structural Biology Laboratory is a state-of-the-art cryo-EM facility that houses a TFS Titan Krios and a TFS Glacios. The Krios is equipped with a Gatan BioContinuum imaging filter and K3 direct electron detector, enabling its use for high-resolution single-particle and tomographic imaging of macromolecular machines. The TFS Glacios is equipped with a TFS Falcon IV direct electron detector for high-resolution single-particle imaging and a TFS CETA-D camera for high-resolution micro -ED data. The facility also houses the equipment required for high-resolution structure determination of thin vitrified samples.
Services Offered
- Cryo-electron microscopy for macromolecular imaging
- High-resolution structure determination
- Sample preparation for cryo-EM
- Data analysis and visualization for structural biology research
