The Mouse Genetic Engineering Facility (MGEF) provides expert advice and custom services to generate, cryopreserve, and rederive genetically engineered mice for understanding mammalian gene function and human disease. The MGEF serves as a central hub for mouse genetics at UT by providing precision mouse models and transgenic services, engaging in teaching, training, and collaborative projects, and undertaking research that supports the core’s mission. The facility is a key resource for researchers across various disciplines, including those studying alcohol addiction, neurodegeneration, immunology, cancer, and developmental disorders.

Services Offered

• Design and generation of precision mouse models
• Cryopreservation of mouse lines
• Cryorecovery of mouse models from repositories
• Embryo manipulation for -omic studies

The Microscopy & Flow Cytometry Facility is the unit responsible for providing access to advanced light microscopes, flow cytometers, and cell sorters for research and teaching at the University. The facility supports users from all disciplines, offering both standard and high-end instrumentation. In addition to assisted use, the facility provides training on equipment and consultations to help researchers optimize their use of the available tools. Staff scientists work closely with investigators, ensuring access to the expertise and resources needed for cutting-edge imaging research.

Services Offered

• Light microscopy
• Confocal and fluorescence microscopy
• Flow cytometry
• Cell sorting
• Analysis workstations
• Training in microscopy and flow cytometry techniques
• Consultation on experimental design for microscopy and flow cytometry studies

The Biomedical Research Computing Facility’s (BRCF) at UT Austin provide specialized computational support for bioinformatics, genomics, and large-scale biological data analysis. This core facility offers high-performance computing infrastructure and software tools tailored to meet the unique needs of computational biology research. Services include data storage, bioinformatics software access, custom workflow development, and consultation on data analysis strategies. CBB staff work closely with researchers to optimize data processing, ensuring efficient and accurate analysis for projects ranging from genomics to structural biology, making it a critical resource for advancing computational research across disciplines.

Services Offered

• High-performance computing resources for biomedical research
• Data storage and management solutions
• Bioinformatics software access
• Custom workflow development
• Data analysis consultations
• Training in computational tools

The Biomedical Imaging Center (BIC) is an interdisciplinary, multimodal imaging facility that supports human and preclinical imaging research at the University of Texas and the wider community. The BIC spans 3 locations in the Norman Hackerman (NHB) and the Health Discovery (HDB) Buildings on the UT campus and hosts a range of systems for MRI, PET, CT and optical imaging. The Center accommodates both independent and assisted use (for human MRI and PET/CT) is on its instruments and provides in-house training in scanner safety and operation for independent users. The facility also supports a range of task / response paradigms for functional MRI (fMRI) studies and provides back-end support for data archiving, management and common analyses.

Services Offered

• Basic, translational and clinical-research involving human or preclinical imaging
• Initial consultation on establishing an imaging research project or program at BIC
• Development / implementation of MRI / fMRI protocols on our 3T and 7T systems
• Ongoing project advice and technical support for the imaging systems and ancillary equipment
• Educational courses on imaging physics and technology
• Training in scanner safety including MRI Level 1 certification
• Training in scanner-operation for our systems including MRI Level 2 certification
• Assisted scanning on the Siemens Prisma, Siemens Vida and GE Discovery systems
• Post-study support for data archiving, management and common analyses