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Thermo Orbitrap Ascend Tribrid with Vanquish Neo

The Thermo Orbitrap Ascend Tribid Mass Spectrometer is a state-of-the-art Tribrid mass spectrometer offering flexibility and depth for advanced proteomics and structural biology studies. Coupled with the Vanquish Neo UPLC system, it supports high-sensitivity peptide and protein analysis across a broad mass range.

Applications

  • Native protein and complex structural analysis
  • Advanced top-down and middle-down proteomics
  • High-resolution peptide mapping and PTM analysis
  • Ultra-sensitive LC-MS/MS workflows for complex samples

Features

Thermo Orbitrap Ascend Tribid Mass Spectrometer

  • Mass Analyzers: Quadrupole, Linear ion trap and Orbitrap mass analyzers
  • Detectors: Ion Trap, Orbitrap mass analyzer
  • Fragmentation/Activation: CID, HCD, ETD, EThcD, ETciD, and PTCR
  • Extended High Mass Range MSn (HMRn+) for structural analysis of native protein complexes (Ion Trap isolation up to m/z 8000 with HMRn+)
  • Proton Transfer Charge Reduction (PTCR) for simplification of complex spectra and improved top-down data interpretation

Vanquish Neo UPLC System

  • Nanoflow to 100 ul/min flow rate
  • Peptide or protein separation
  • Trap and elute or direct inject loading autosampler
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Thermo Orbitrap Ascend Tribrid with Vanquish Neo