Method of Preparation and Composition of Micro and Nano Devices for Recognition and Signaling

Nanotechnologies : Life Science Apps

Available for licensing

Inventors

  • Nicholas Peppas, Sc.D. , Biomedical Engineering
  • Carolyn Bayer , Biomedical Engineering

Background/unmet need

In medical diagnostics, the speed and precision with which a condition is detected directly impacts the prognosis of a patient. Point-of-care (POC) diagnostic devices, which enable diagnostic testing at the site of care, can enhance patient outcomes by abbreviating analysis times by eliminating the need to transport samples to onsite or off-site laboratories for testing. The development of micro or minaturized total analysis systems has had a profound impact on the POC diagnostic tools. Future development of biocompatible materials that will enhance the capabilities of these devices would revolutionize the way healthcare is administered.

Invention Description

Researchers at the University of Texas have developed a novel label-free detection chemistry method for diagnosis of a broad range of biological and chemical analytes. This is accomplished through a novel method of preparation and composition of recognition, conductive polymers with electrical signal capabilities called RECONGEL. This versatile platform technology can selectively sense an analyte and upon recognition emit an electric signal without the need for an additional interface. The durable and stable synthetic polymer material is capable of a broad range of form factors including films, coatings, or microparticles. The system is customizable to detect minute levels of a single or multiple biological molecules with high selectivity and affinity. The RECONGEL systems can also be used in association with standard photolithography processes to create novel biosensors with sensing/recognitive capabilities, as well as associated signal transmitting capabilities. This technology is applicable to a number of markets of interests including personal health monitoring, medical devices and diagnostics, food and beverage testing, and industrial processing.

Benefits/Advantages

  • ”Smart ” biodegradable material
  • Adaptable to many form factors.
  • Customizable for high affinity/selection of analytes.

Features

    Can detect passive binding of a protein.

Market potential/applications

This technology is applicable to a number of markets of interests including personal health monitoring, medical devices and diagnostics, food and beverage testing, and industrial processing.

IP Status